Rapid Recovery after Reparation of Full-Thickness Chondral Defects of the Knee with the Use of Hyaluronan (HA)-Based 3-D Scaffold

نویسندگان

چکیده

Articular cartilage injuries are found in up to 60% of patients who undergo an arthroscopic knee procedure, and those that totally affect articular (grade IV) have limited regenerative capacity extended time for recovery. 3-D scaffolds represent a novel solution address this type injury. Our purpose was analyze the MRI findings functional status underwent repair chondral defects either by microfractures or Hyaluronan (HA) scaffolding. We conducted retrospective study with defects. The outcomes analyzed included anatomical changes evaluated Henderson score (based on findings) at baseline, 6, 12 months after surgery, improvement functionality Modified Cincinnati Knee Rating System (MCKRS) baseline 6 surgery. Clinical demographic characteristics were similar both groups. There statistically significant scaffold-treated group versus microfracture (p < 0.0001). Improvement functionality, measured MCKRS, more frequently group. In conclusion, use HA scaffolding superior, faster recovery evident surgery progressed full all year Future studies randomized design might help support our findings. This provides level III evidence.

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ژورنال

عنوان ژورنال: Journal of Functional Biomaterials

سال: 2023

ISSN: ['2079-4983']

DOI: https://doi.org/10.3390/jfb14100491